Peptide Database

Peptide NameCycloviolacin O1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC123H189N29O37S6

DescriptionStandard

        GIPCGEGCVYLPCFTAPLGCSCSSKVCY
    

Molecular Weight2858.38 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0107

GRAVY Index0.74

Hydrophobic Moment 0.23

Boman Index0.33

Instability Index21.36

Aliphatic Index 66.07

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1007.35

LogP -10.93

H-bond Donors 40.0

H-bond Acceptors 43.0

Rotatable Bonds 83.0

Heavy Atoms 195.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151354 VERIFIED: YES

Provenance & Taxonomy

OrganismViola baoshanensis [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)