Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC628H1027N177O195S3

DescriptionStandard

        MVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEI
    

Molecular Weight14273.14 Da

Isoelectric Point (pI)4.91

Net Charge (pH 7.0)-4.31

Net Charge (pH 7.4) -4.64

Charge Density (pH 7.0) -0.0303

GRAVY Index0.14

Hydrophobic Moment 0.77

Boman Index0.17

Instability Index52.09

Aliphatic Index 97.68

Aromaticity 0.0141

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5745.71

LogP -66.04

H-bond Donors 186.0

H-bond Acceptors 196.0

Rotatable Bonds 437.0

Heavy Atoms 1003.0

Ring Count 23.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252469 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella newport [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli