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MYP_079094
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Basic Information
Defensin-derived D-Peptide A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C53H95N21O11
Standard
Sequence
RLYLRIGRR
Physicochemical Analysis
1202.46 Da
12.00
3.76
3.55
0.4177
-0.84
0.99
-0.65
93.93
130.00
0.1111
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
563.95
-3.95
23.0
15.0
41.0
85.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274055 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19154767/
RECORD: Rec_0292847 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Anticancer Cytotoxic
Human squamous carcinoma RERF-LC-AI
605
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0294204 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19154767/
RECORD: Rec_0299797 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Mouse myeloma P3-X63-Ag8.653
96
IC50
PMID19584534;15003352;19154767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
RECORD: Rec_0299873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei brucei GUTat3.1
205±22 μM
MIC; Cell numbers counted by Z1 Coulter Counter
PMID19584534 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19584534/
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