Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC371H600N114O110S8

DescriptionStandard

        MKKAFKRSKIEETSKCHQGYGVCRDRCRKDETEVHFCRNNRRCCINSDSTILTNVIAKEIEWPRLITTSMPFY
    

Molecular Weight8673.95 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)5.63

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0771

GRAVY Index-0.77

Hydrophobic Moment 0.53

Boman Index-0.27

Instability Index61.38

Aliphatic Index 57.40

Aromaticity 0.0822

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3705.57

LogP -40.04

H-bond Donors 139.0

H-bond Acceptors 126.0

Rotatable Bonds 296.0

Heavy Atoms 603.0

Ring Count 11.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022723 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx canadensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal