Peptide Database

Peptide NameRugosin-RN

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune modulation ▸ Mast cell modulation

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC153H276N42O46S2

DescriptionStandard

        SIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC
    

Molecular Weight3504.21 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.1042

GRAVY Index0.26

Hydrophobic Moment 0.55

Boman Index0.02

Instability Index-1.01

Aliphatic Index 124.24

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1445.82

LogP -14.25

H-bond Donors 54.0

H-bond Acceptors 52.0

Rotatable Bonds 126.0

Heavy Atoms 243.0

Ring Count 0.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403586 VERIFIED: YES

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC25923

Activity4.69 μg/mL

MethodMIC

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