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MYP_079011
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Basic Information
Dermcidin DCD-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
47 amino acids
C204H348N56O70
Standard
Sequence
SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV
Physicochemical Analysis
4705.28 Da
5.07
-2.44
-2.72
-0.0520
-0.11
0.62
0.04
10.13
109.79
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2029.36
-21.97
69.0
69.0
169.0
330.0
1.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0178735 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-Lys: N6-acetyllysine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Host defense
PaperPDB 2KSG structural record; NMR; chain A; residues 1-47
RECORD: Rec_0179114 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Proteolytic
Enterococcus faecalis
PaperPubMed PMID: 11694882 | PubMed PMID: 17448443 | PubMed PMID: 20510021 PMID11694882;17448443;20510021 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11694882/
RECORD: Rec_0312327 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20120213764A1/en PatentUS 2012/0213764 A1
RECORD: Rec_0323437 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Dermicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
E. coli
PMID11694882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11694882/
RECORD: Rec_0325309 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Dermicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
E. faecalis
PMID11694882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11694882/
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