Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC924H1443N249O252S9

DescriptionStandard

        VAHEPMLLLAITDFVANSAAFTYFTAGALHRNISSDILPRRFPLQLRTKSMGAFAPQLQKLYPDHPMELHLSARKQPLFSCHPATLHGALFSSAEAFVVLPDATRVPAFLLNIDANVTGKPTTSGNRLRGTVSLKGGAAYAMAPSVCPMPGSGGLSVPQVKKLENLLKFSLWLFGVPWANSECCPHPDP
    

Molecular Weight20360.44 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)5.31

Net Charge (pH 7.4) 4.66

Charge Density (pH 7.0) 0.0281

GRAVY Index0.10

Hydrophobic Moment 0.57

Boman Index0.15

Instability Index47.01

Aliphatic Index 88.36

Aromaticity 0.0847

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7796.63

LogP -90.69

H-bond Donors 267.0

H-bond Acceptors 273.0

Rotatable Bonds 637.0

Heavy Atoms 1434.0

Ring Count 44.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389724 VERIFIED: NO

Provenance & Taxonomy

OrganismJacana jacana (Wattled jacana) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria