Peptide Database

Peptide NameDQ2-gamma-V gamma-Glia (p78 p97; E81 and E89)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H158N28O34

DescriptionStandard

        LQPEQPFPQQPEQPYPQQPQ
    

Molecular Weight2404.59 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1118

GRAVY Index-2.04

Hydrophobic Moment 0.34

Boman Index-0.25

Instability Index184.17

Aliphatic Index 19.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 994.24

LogP -9.76

H-bond Donors 25.0

H-bond Acceptors 32.0

Rotatable Bonds 68.0

Heavy Atoms 171.0

Ring Count 9.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270636 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E81; Reported substitutions/positions: E89

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay

RECORD: Rec_0370731 VERIFIED: YES