Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC470H765N131O124S8

DescriptionStandard

        MAADLEPLKSERPHHPLQSQLGSQPAIRLYYLLFALLFLFLLPVPGNGNIISGLQKYYCKIRSGQCALIGCLPKEEQIDCCSLRGRKCCRKKK
    

Molecular Weight10491.43 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0818

GRAVY Index-0.09

Hydrophobic Moment 0.52

Boman Index0.00

Instability Index59.34

Aliphatic Index 100.75

Aromaticity 0.0753

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4086.73

LogP -33.23

H-bond Donors 146.0

H-bond Acceptors 142.0

Rotatable Bonds 351.0

Heavy Atoms 733.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0051046 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence