Peptide Database

Peptide NameGlia-alpha2 (p60-p76; E66)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC99H139N21O26

DescriptionStandard

        QPFPQPELPYPQPQLPY
    

Molecular Weight2039.29 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0729

GRAVY Index-1.23

Hydrophobic Moment 0.16

Boman Index0.03

Instability Index140.19

Aliphatic Index 45.88

Aromaticity 0.1765

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 717.51

LogP -3.14

H-bond Donors 18.0

H-bond Acceptors 25.0

Rotatable Bonds 51.0

Heavy Atoms 146.0

Ring Count 10.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052145 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E66

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay