Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC365H600N112O99S9

DescriptionStandard

        MRIPVLLLTTFLMLFQAVRNDLDADRICGYGTSRCRRYCKRQEIRIGRCPNTYPCCLKKWRDSSLNPMKDK
    

Molecular Weight8429.94 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.1189

GRAVY Index-0.48

Hydrophobic Moment 0.64

Boman Index-0.22

Instability Index37.65

Aliphatic Index 76.90

Aromaticity 0.0845

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3471.60

LogP -32.78

H-bond Donors 131.0

H-bond Acceptors 117.0

Rotatable Bonds 282.0

Heavy Atoms 585.0

Ring Count 11.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100072 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence