Peptide Database

Peptide NameZinc metalloproteinase-disintegrin-like BjussuMP-1 (EC 3.4.24.-) (BjussuMP-I) (Snake venom metalloproteinase) (SVMP)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Protease

Enzyme / Catalytic activity ▸ Protease ▸ Metalloprotease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length547 amino acids

Chemical FormulaC2698H4149N753O842S43

DescriptionStandard

        EFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGRQITTYPPVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWEYEEPIKKASKLVVTAEQQKFPYRYVEIVVVVDRRMVTKYNGDLKKIRKWVYELVNIVNNIYRSLNVHVALVGLEIWSKGDKITVQPDSDYTLNSFGEWRERDLLPRKKHDNAQLLTAVVFDGPTIGRAYIAGMCDPRHSVGVVMDHSKENLQVAVTMAHELGHNLGMEHDENQCHCDAPSCVMASVLSVVLSYEFSDCSQNQYQTYLTKHNPQCILNEPLLTVSGNELLEAGEECDCGAPENPCCDAATCKLRPGAQCAEGLCCDQCRFKGAGKICRRARGDNPDDRCTGQSADCPRNRFHRNGQPCLYNHGYCYNGKCPIMFYQCYFLFGSNATVAEDDCFNNNKKGDKYFYCRKENEKYIPCAQEDVKCGRLFCDNKKYPCHYNYSEDLDFGMVDHGTKCADGKVCSNRQCVDVNEAYKSTTVFSLI
    

Molecular Weight61984.14 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-15.76

Net Charge (pH 7.4) -17.58

Charge Density (pH 7.0) -0.0288

GRAVY Index-0.58

Hydrophobic Moment 0.78

Boman Index-0.08

Instability Index32.30

Aliphatic Index 66.62

Aromaticity 0.0951

Extinction Coeff. Reduced 68190.00

Extinction Coeff. Oxidized 70315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248962 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararacussu [Animal]

FamilyVenom metalloproteinase (M12B); P-III subfamily; P-IIIa sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Hydrolase Metalloprotease Protease Antiplatelet Toxin Proteolytic Non-hemolytic

TargetNo Target Organism Found