Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC394H648N108O99S10

DescriptionStandard

        MAMRSVLLVLVVLVLLSCVPPVRSGPNIYIRRMFASCWRLQGYCRKKCSKGEEYHILCDTSYVCCIDKKHLPILVGK
    

Molecular Weight8802.67 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)7.60

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0987

GRAVY Index0.40

Hydrophobic Moment 0.75

Boman Index0.09

Instability Index70.46

Aliphatic Index 112.47

Aromaticity 0.0779

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3298.34

LogP -22.60

H-bond Donors 125.0

H-bond Acceptors 119.0

Rotatable Bonds 290.0

Heavy Atoms 611.0

Ring Count 13.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103231 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence