Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC927H1396N206O285S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGIVYPSGNYTGPPYVASPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAEYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIAPNIFDQKLMGSLCLNR
    

Molecular Weight20242.73 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.23

Net Charge (pH 7.4) -16.51

Charge Density (pH 7.0) -0.0887

GRAVY Index0.27

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index47.63

Aliphatic Index 91.69

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7744.02

LogP -81.92

H-bond Donors 262.0

H-bond Acceptors 277.0

Rotatable Bonds 637.0

Heavy Atoms 1426.0

Ring Count 38.0

Amide Bonds 196.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0327924 VERIFIED: NO

Provenance & Taxonomy

OrganismHalcyon senegalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria