‹ ›
MYP_078851
← PREVIOUS NEXT → BACK
Basic Information
M-Cecropin-B [M12V], HB12, SB-37 AMD
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
38 amino acids
C188H320N54O45S
Standard
Sequence
MPKWKVFKKIEKVGRNIRNGIVKAGPAIAVLGEAKALG
Physicochemical Analysis
4088.95 Da
10.73
6.50
6.27
0.1710
-0.01
0.91
0.05
31.93
105.26
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1604.95
-10.86
55.0
53.0
142.0
288.0
5.0
39.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0175652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
60 μg/mL
MBC
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0177282 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human colon adenocarcinoma SW480
1000 μg/mL
LD50
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0179196 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
SB
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum Sierra- Leone1/CDC isolate
50 μM
IC50; [3H] Hypoxanthine incorporation assay
PMID3049204 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3049204/
RECORD: Rec_0184041 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
SB
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Trypanosoma cruzi
Trypanosoma cruzi
100 μM
IC50; Microscopy (Wright’s staining)
PMID3049204 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3049204/
RECORD: Rec_0187335 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human cervical carcinoma HeLa S3
150 μg/mL
LD50
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
FIRST PREV 1 ... 5 6 7 8 9 ... 12 NEXT LAST
Showing 5 records on this page · Page 7 of 12