Peptide Database

Peptide NameMesencephalic astrocyte-derived neurotrophic factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC802H1307N219O241S9

DescriptionStandard

        LRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
    

Molecular Weight18161.87 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)3.88

Net Charge (pH 7.4) 3.38

Charge Density (pH 7.0) 0.0245

GRAVY Index-0.59

Hydrophobic Moment 0.75

Boman Index-0.17

Instability Index27.76

Aliphatic Index 87.09

Aromaticity 0.0696

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7515.53

LogP -66.00

H-bond Donors 268.0

H-bond Acceptors 256.0

Rotatable Bonds 630.0

Heavy Atoms 1271.0

Ring Count 20.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027957 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyARMET family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-93; 9-82; 40-51; 127-130

Other Mods52-Tyr: Phosphotyrosine

Bio-Activity Profile

Function

Cytokine Growth factor ARMET family