Peptide Database

Peptide NameHepcidin isoform 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC420H653N113O122S14

DescriptionStandard

        MKTFSVAVAVAVMLAFICLQESSAVPVNEEQELEQQIYFDDPEMPVDSWKMPYHLRQKRHSSAAKCQFCCRCCPDMIGCGVCCRF
    

Molecular Weight9686.27 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.87

Charge Density (pH 7.0) -0.0282

GRAVY Index0.04

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index76.05

Aliphatic Index 67.65

Aromaticity 0.0941

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3745.30

LogP -34.02

H-bond Donors 135.0

H-bond Acceptors 136.0

Rotatable Bonds 315.0

Heavy Atoms 669.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423099 VERIFIED: NO

Provenance & Taxonomy

OrganismLarimichthys crocea [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence