Peptide Database

Peptide Name[Ile5,Trp23]PTHrP-(5-36)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC177H284N54O45

DescriptionStandard

        IQLLHDKGKSIQDLRRRFWLHHLIAEIHTAEI
    

Molecular Weight3888.48 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)1.11

Net Charge (pH 7.4) 0.70

Charge Density (pH 7.0) 0.0348

GRAVY Index-0.31

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index66.96

Aliphatic Index 128.12

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1609.51

LogP -9.98

H-bond Donors 57.0

H-bond Acceptors 50.0

Rotatable Bonds 133.0

Heavy Atoms 276.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367039 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetPTH1 receptor (Human); PTH2 receptor (Human)