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MYP_078732
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Basic Information
Ascalin
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiviral
Antiviral ▸ Anti-HIV
Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C28H41N9O11S
Standard
Sequence
YQCGQGG
Physicochemical Analysis
711.74 Da
5.52
-0.25
-0.47
-0.0358
-1.00
0.31
0.04
15.43
0.00
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
344.33
-5.39
12.0
12.0
22.0
49.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050910 VERIFIED: YES
Provenance & Taxonomy
Allium cepa var. aggregatum [Plant]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
HIV-1 reverse transcriptase
10 μM
IC50
PMID12126728 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12126728/
RECORD: Rec_0056219 VERIFIED: YES
Provenance & Taxonomy
Allium ascalonicum [Plant]
Ascalin
1476995
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Reverse transcriptase inhibition
10 μM
IC50
PaperAscalin, a new anti-fungal peptide with human immunodeficiency virus type 1 reverse transcriptase-inhibiting activity from shallot bulbs. PMID12126728 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12126728/
RECORD: Rec_0125446 VERIFIED: YES
Provenance & Taxonomy
Allium cepa var. aggregatum [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
HIV-1 reverse transcriptase
10 μM
IC50
PaperPubMed PMID: 12126728 PMID12126728 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12126728/
RECORD: Rec_0214774 VERIFIED: NO
Provenance & Taxonomy
Allium cepa var. aggregatum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Fungicide Antiviral Anti-HIV Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID12126728 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12126728/; https://www.uniprot.org/uniprotkb/P84071/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0278184 VERIFIED: YES
Provenance & Taxonomy
Allium cepa var. aggregatum [Plant]
Ascalin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Hemolytic Cytotoxic Antiviral Anti-HIV
HIV-1 reverse transcriptase
10 μM
IC50
PaperPubMed PMID 12126728 PMID12126728 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12126728/
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