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MYP_078706
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Basic Information
Polybia MP3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
14 amino acids
C77H129N17O19S2
Standard
Sequence
IDWLKLGKMVMDVL
Physicochemical Analysis
1661.08 Da
5.96
-0.24
-0.45
-0.0171
0.86
0.57
0.32
23.19
152.86
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
584.05
0.27
20.0
21.0
57.0
115.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0309725 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
Escherichia coli
38 μM
MIC
PaperPubMed PMID: 19463874 PMID19463874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463874/
RECORD: Rec_0332551 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
38 μM
MIC
PMID19463874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463874/
RECORD: Rec_0346083 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
38 μM
MIC
PMID19463874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463874/
RECORD: Rec_0359158 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0366956 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
Pseudomonas aeruginosa
310 μM
MIC
PaperPubMed PMID: 19463874 PMID19463874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463874/
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