Peptide Database

Peptide NameCycloviolacin O18

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC123H200N30O38S6

DescriptionStandard

        GIPCAESCVYIPCLTSAIGCSCKSKVCY
    

Molecular Weight2899.47 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0250

GRAVY Index0.80

Hydrophobic Moment 0.32

Boman Index0.27

Instability Index27.79

Aliphatic Index 83.57

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.39

LogP -11.75

H-bond Donors 43.0

H-bond Acceptors 45.0

Rotatable Bonds 89.0

Heavy Atoms 197.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125368 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)