Peptide Database

Peptide NameMoronecidin (Piscidin-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC398H620N118O120S4

DescriptionStandard

        MKCATLSLVLSMVVLMAEPGDAFFHHIFRGIVHVGKTIHKLVTGGKAEQDQQDQQYQQDQQDQQAQQYQRFNRERAAFD
    

Molecular Weight9106.16 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0145

GRAVY Index-0.61

Hydrophobic Moment 0.73

Boman Index-0.09

Instability Index42.36

Aliphatic Index 70.38

Aromaticity 0.0886

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3914.39

LogP -40.79

H-bond Donors 131.0

H-bond Acceptors 127.0

Rotatable Bonds 312.0

Heavy Atoms 640.0

Ring Count 12.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361047 VERIFIED: YES

Provenance & Taxonomy

OrganismMorone chrysops [other]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiviral Antifungal Anti-HSV Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria