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MYP_078675
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Basic Information
LIB24
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
27 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
MRPEIWIAQELDRDGDENNAYYARRVX
Physicochemical Analysis
0.00 Da
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011439 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical or ambiguous residue annotation [Modified]
None
None
Contains X placeholder residue(s) at position(s) 27; identity unresolved
Bio-Activity Profile
Mcl-1/Bcl-xL binding Peptide-protein interaction Protein-binding Antimicrobial Anticancer
Mcl-1; Bcl-xL
peptide-protein binding screen
PaperDeterminants of BH3 binding specificity for Mcl-1 versus Bcl-xL. J Mol Biol. 2010 May 21;398(5):747-62. doi: 10.1016/j.jmb.2010.03.058. PMID: 20363230. PMID20363230 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20363230/
RECORD: Rec_0073785 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical or ambiguous residue annotation [Modified]
None
None
Contains X placeholder residue(s) at position(s) 27; identity unresolved
Bio-Activity Profile
Mcl-1/Bcl-xL binding Peptide-protein interaction Protein-binding Antimicrobial Anticancer Cytotoxic
Mcl-1; Bcl-xL
peptide-protein binding screen
PaperDeterminants of BH3 binding specificity for Mcl-1 versus Bcl-xL. J Mol Biol. 2010 May 21;398(5):747-62. doi: 10.1016/j.jmb.2010.03.058. PMID: 20363230. PMID20363230 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20363230/
RECORD: Rec_0285458 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical or ambiguous residue annotation [Modified]
None
None
Contains X placeholder residue(s) at position(s) 27; identity unresolved
Bio-Activity Profile
Mcl-1/Bcl-xL binding Peptide-protein interaction Protein-binding Antimicrobial Anticancer Hemolytic
Mcl-1; Bcl-xL
peptide-protein binding screen
PaperDeterminants of BH3 binding specificity for Mcl-1 versus Bcl-xL. J Mol Biol. 2010 May 21;398(5):747-62. doi: 10.1016/j.jmb.2010.03.058. PMID: 20363230. PMID20363230 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20363230/