Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length662 amino acids

Chemical FormulaC3043H4973N893O954S19

DescriptionStandard

        MMADNQPIPLTPAPPGMTSLGVNADGEEVMTVVGGGGGTGFSGGQANIVPGSGSVQADLGKKTLSRLQAESSAAIHATAKWSTKNLAKTQAAQAERVRASMAAQQAARASRDRLTQQLKDVTNRALQKGRAGPSITDLAHATNAAMAAAAAQEGALRAAKKKAEKAEKAWQAALRQQEEAQRQQAEVERKLKEAREREAAAKVKADADQAAAEKAESEVRAKAEAERRKAEEARKALYAKAGVQDTPVYTQDMVKAAAALVMAPGAALLNRAPGMIQMSAVAIQVQAALPPIVSAVMTATAEFSGWISSALWRAVVGVSGAATATTAGAMVAAASTIFFSPRAGGGNDSKVPGRDIEMMAAQACLFTAGKLSIEPGMKSVGLPVRGYITKESDGRQSVMLVKTGSGDVFATVPVLNAVRDKATGLDKITVPAVAGAPSRTILVNPVPVGPTAPSHTGNGSPVPVTLVHTGTELKKADSIVTTTLPVADIPALQDFIYWQPDVTGTGVEPIYVMLRPYGETNAKGKYSGRNYNTEKAGGPIQNLDWKTAKIDRTGVGKVKLHTGRFAESDANKVMIERLEKILKGELQVTDIDKRFYTHEIRELERYRNLGIKDGSVPNNQGEVWNNTHTATLEDYRLGNSETLLYTPEALKAAEEQELRELK
    

Molecular Weight69941.68 Da

Isoelectric Point (pI)9.29

Net Charge (pH 7.0)11.20

Net Charge (pH 7.4) 10.43

Charge Density (pH 7.0) 0.0169

GRAVY Index-0.31

Hydrophobic Moment 0.67

Boman Index-0.01

Instability Index33.26

Aliphatic Index 79.89

Aromaticity 0.0423

Extinction Coeff. Reduced 56380.00

Extinction Coeff. Oxidized 56380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013913 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella spallanzanii [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)