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MYP_078662
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Basic Information
Histone H2B-1(HLP-1) (fish, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Standard
19 amino acids
C85H151N25O25
Standard
Sequence
PDPAKTAPKKGSKKAVTKA
Physicochemical Analysis
1923.26 Da
10.30
4.95
4.89
0.2607
-1.21
0.50
-0.30
16.84
36.32
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
809.66
-10.07
28.0
30.0
65.0
135.0
3.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078393 VERIFIED: YES
Provenance & Taxonomy
Ictalurus punctatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.37±0.023 μM
MIC
PMID9645227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9645227/
RECORD: Rec_0104362 VERIFIED: YES
Provenance & Taxonomy
Ictalurus punctatus [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
ory to two A. hydrophila isolates
50 μg/mL
MIC
PaperAntimicrobial activity in the skin of the channel catfish Ictalurus punctatus: characterization of broad-spectrum histone-like antimicrobial proteins.
RECORD: Rec_0132383 VERIFIED: NO
Provenance & Taxonomy
Ictalurus punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli D31
Evidence URLhttps://www.uniprot.org/uniprotkb/P81903/entry
RECORD: Rec_0163655 VERIFIED: NO
Provenance & Taxonomy
Ictalurus punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Vibrio alginolyticus
Evidence URLhttps://www.uniprot.org/uniprotkb/P81903/entry
RECORD: Rec_0206001 VERIFIED: YES
Provenance & Taxonomy
Ictalurus punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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