Peptide Database

Peptide NameKaliotoxin

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC171H289N55O49S8

DescriptionStandard

        GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK
    

Molecular Weight4155.98 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.1523

GRAVY Index-0.57

Hydrophobic Moment 0.72

Boman Index-0.19

Instability Index49.08

Aliphatic Index 38.42

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1686.81

LogP -20.88

H-bond Donors 63.0

H-bond Acceptors 64.0

Rotatable Bonds 141.0

Heavy Atoms 283.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0133148 VERIFIED: NO

Provenance & Taxonomy

OrganismAndroctonus australis [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28, 14-33, 18-35

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0206210 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus mauritanicus mauritanicus [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28; 14-33; 18-35

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense