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MYP_078646
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
12 amino acids
C52H92N12O16
Standard
Sequence
GLLDALSGILGL
Physicochemical Analysis
1141.36 Da
4.05
-1.24
-1.44
-0.1032
1.65
0.36
0.64
18.14
203.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
440.95
-2.61
15.0
15.0
38.0
80.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249927 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0255113 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Frenatin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0269115 VERIFIED: YES
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
25 μg/mL
MIC
PMID9225251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9225251/
RECORD: Rec_0326301 VERIFIED: NO
Provenance & Taxonomy
Litoria infrafrenata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID9225251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9225251/
RECORD: Rec_0361507 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
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