Peptide Database

Peptide NameP12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC135H219N39O21

DescriptionStandard

        VWKRWVVRKWKWVKKKVKKK
    

Molecular Weight2724.43 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.72

Net Charge (pH 7.4) 10.50

Charge Density (pH 7.0) 0.5363

GRAVY Index-1.33

Hydrophobic Moment 0.64

Boman Index-0.50

Instability Index38.83

Aliphatic Index 72.50

Aromaticity 0.2000

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1037.36

LogP -0.53

H-bond Donors 40.0

H-bond Acceptors 32.0

Rotatable Bonds 96.0

Heavy Atoms 195.0

Ring Count 8.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412221 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetStaphylococcus aureus ATCC 25923

Activity64 μg/mL

MethodMIC

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