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MYP_078590
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Basic Information
Defensin D1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
50 amino acids
C232H355N69O70S8
Standard
Sequence
KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKPPAHRCICYYEC
Physicochemical Analysis
5487.24 Da
8.48
2.86
2.42
0.0571
-0.60
0.37
-0.09
28.32
35.20
0.1000
9970.00
10470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2230.21
-26.90
85.0
83.0
176.0
379.0
11.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0127419 VERIFIED: YES
Provenance & Taxonomy
Nigella sativa [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium culmorum
6.9 μg/mL
IC50
PaperNovel antifungal defensins from Nigella sativa L. seeds
RECORD: Rec_0137077 VERIFIED: YES
Provenance & Taxonomy
Nigella sativa [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aspergillus niger
3.5 μg/mL
IC50
PMID21144761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21144761/
RECORD: Rec_0144226 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID8422949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0175526 VERIFIED: YES
Provenance & Taxonomy
Nigella sativa [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Botrytis cinerea
PMID21144761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21144761/
RECORD: Rec_0177765 VERIFIED: YES
Provenance & Taxonomy
Nigella sativa [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Antifungal Non-hemolytic
Fusarium oxysporum
PMID21144761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21144761/
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