Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H886N148O164S3

DescriptionStandard

        PDLNGYEKFGLGNVKYNISRIHITAVEFPSASISLIPGTGIKLVIGNASLAVNMNWNIRTWMFKDSGRSTVYISKVLVTAIFSTLLDHTGHPSISLTSCRTTSGDIDIKLSGKS
    

Molecular Weight12328.04 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0369

GRAVY Index0.12

Hydrophobic Moment 0.53

Boman Index0.15

Instability Index22.18

Aliphatic Index 100.88

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4987.79

LogP -53.33

H-bond Donors 179.0

H-bond Acceptors 174.0

Rotatable Bonds 407.0

Heavy Atoms 868.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296453 VERIFIED: NO

Provenance & Taxonomy

OrganismBucco capensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria