Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC770H1241N229O228S4

DescriptionStandard

        SSLWLLLLGLVVPSASAQDLSYREAVLRAVDQFNERSSEANLYRLLELDPPPEQDVEHPGARKPVSFTVKETVCPRTTPQPPEQCDFKENGLVKQCVGTVTRYWIRGDFDITCNNIQSAGLFRRLRDSIRRGQQKILEKARRIGERIKDIFRG
    

Molecular Weight17482.75 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.0231

GRAVY Index-0.52

Hydrophobic Moment 0.98

Boman Index-0.15

Instability Index47.64

Aliphatic Index 87.25

Aromaticity 0.0719

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7447.18

LogP -75.73

H-bond Donors 263.0

H-bond Acceptors 237.0

Rotatable Bonds 583.0

Heavy Atoms 1231.0

Ring Count 24.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232601 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence