Peptide Database

Peptide NameSLAY-screened peptide P68

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC117H192N46O25

DescriptionStandard

        RRVRHRILSDIRVAHYRRWP
    

Molecular Weight2643.07 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.93

Net Charge (pH 7.4) 5.63

Charge Density (pH 7.0) 0.2967

GRAVY Index-1.15

Hydrophobic Moment 0.60

Boman Index-0.59

Instability Index123.95

Aliphatic Index 92.50

Aromaticity 0.1000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1191.64

LogP -9.50

H-bond Donors 47.0

H-bond Acceptors 33.0

Rotatable Bonds 85.0

Heavy Atoms 188.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425254 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/