Peptide Database

Peptide NameBeta-defensin 39

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC374H606N108O107S7

DescriptionStandard

        MKISYFLLLILSLGSSQINPVSGDDSIQCFQKNNTCHTNQCPYFQDEIGTCYDKRGKCCQKRLLHIRVPRKKKV
    

Molecular Weight8551.93 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0893

GRAVY Index-0.46

Hydrophobic Moment 0.51

Boman Index-0.12

Instability Index39.08

Aliphatic Index 80.27

Aromaticity 0.0811

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3534.53

LogP -36.72

H-bond Donors 127.0

H-bond Acceptors 123.0

Rotatable Bonds 292.0

Heavy Atoms 596.0

Ring Count 11.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103008 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence