Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 2.12

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC180H303N55O50S7

DescriptionStandard

        TIINVKCTSPKQCLPPCKEIYGRHAGAKCMNGKCHCSKI
    

Molecular Weight4262.13 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.51

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.1413

GRAVY Index-0.31

Hydrophobic Moment 0.43

Boman Index-0.07

Instability Index59.67

Aliphatic Index 62.56

Aromaticity 0.0256

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1685.85

LogP -18.96

H-bond Donors 63.0

H-bond Acceptors 65.0

Rotatable Bonds 142.0

Heavy Atoms 292.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359362 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides elegans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-29; 13-34; 17-36

Bio-Activity Profile

Function

Toxin

TargetKv1