Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length568 amino acids

Chemical FormulaC2748H4310N790O859S18

DescriptionStandard

        MGAMGFYLRVGDATTCGGKILTGDETLSWYGVAGALEGDLVTCGKHPGTYIILGGTSDTWDEGRRFAGTLDSFSSCPCRARFIQSIPDGYIRDDTPEERAEKERLSALIRQKEMEKNQEEAAKVLAEERDRNRVFAKSCLREDGCNNAGTEPEPHTNFPRMAFYQALPTEDPSDENDVPQHAQAAKKKNAAEEIPKPKKRSALYKWWHGNHEEMDYQAARAAAASAAHAQMAVEGASVLGLIGGSAITSGTWAIKLGEMAAGLGRVATSGPGAPIAAVLVGMMPGRLNDGEQDFIDRMRLEQMREAPSRVRYTWETDSQGRSVPHGWHTPPGKDAVRVRKMAWDNSRRAYTFTTEEDPRITIIWTPDSSGVNAPSNTGNQTPVRIPNPVIVDPLPEETRLEATTSPAPEEKTFADYILILPLPNIPPIYVYLSKPPVEFLEVGLYSDFEGRSRQGELEVDHIPSAAAVKAYYKSLHPELTPKELRKLSKRVAAIGVPIEVHRNNSETYAGRNTAEKINDQSYDLRKAADENFNFEKSALKEHGATEEQLEEARAKLHQINESVGLYTR
    

Molecular Weight62735.57 Da

Isoelectric Point (pI)5.57

Net Charge (pH 7.0)-13.29

Net Charge (pH 7.4) -14.43

Charge Density (pH 7.0) -0.0234

GRAVY Index-0.61

Hydrophobic Moment 0.78

Boman Index-0.08

Instability Index43.08

Aliphatic Index 69.84

Aromaticity 0.0722

Extinction Coeff. Reduced 76320.00

Extinction Coeff. Oxidized 76695.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136450 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteriaceae bacterium RIT693 [Bacterium]

FamilyPyocin/Colicin

Tax ID2666197

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli