Peptide Database

Peptide NameProgonadoliberin IIA

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC314H501N93O93S2

DescriptionStandard

        QHWSHGWYPGGKREIDVYDSSEVSGEIKLCEAGKCSYLRPQGRNILKTILLDAIIRDSQKRK
    

Molecular Weight7131.03 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)2.92

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0471

GRAVY Index-0.78

Hydrophobic Moment 0.64

Boman Index-0.17

Instability Index65.08

Aliphatic Index 81.77

Aromaticity 0.0806

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3048.46

LogP -29.83

H-bond Donors 110.0

H-bond Acceptors 100.0

Rotatable Bonds 243.0

Heavy Atoms 502.0

Ring Count 11.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117653 VERIFIED: YES

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyProgonadoliberin IIA

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour