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MYP_078373
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Basic Information
Anoplin [T8Beta-Ala]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GLLKRIKXLL
Physicochemical Analysis
0.00 Da
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0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022105 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 19606
128 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0037388 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa[30-40% Killing = 256 microM
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0053166 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 12228
16 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0076193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 8
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa 86
8 μM
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0101989 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(8)=Beta-Ala
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
30 %
Cytotoxicity
PaperPubMed PMID: 32654770 PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
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