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MYP_078305
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Basic Information
Hepcidin-2 (mammals, rodents, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
25 amino acids
C114H178N32O36S8
Standard
Sequence
DINFPICRFCCQCCNKPSCGICCEE
Physicochemical Analysis
2829.35 Da
4.94
-1.31
-1.64
-0.0523
0.21
0.57
0.02
42.10
46.80
0.0800
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1093.46
-12.66
43.0
43.0
89.0
190.0
4.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013186 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 12729891 | PubMed PMID: 16141072 PMID12729891;16141072 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12729891/
RECORD: Rec_0178152 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23; 10-13; 11-19; 14-22
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Hepcidin-2 (Mus musculus): PMID 12729891 PMID12729891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12729891/
RECORD: Rec_0347441 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1901
RECORD: Rec_0396570 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-13; 10-23; 11-22; 14-19
Bio-Activity Profile
Antimicrobial