Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC356H563N109O96S9

DescriptionStandard

        MSYNTGTNMRTLGLIIFALLLLTASQANDTDVQRWTCGYRGLCRKHCYAREYMIGYRGCPRRYRCCALRF
    

Molecular Weight8194.54 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.1075

GRAVY Index-0.22

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index25.00

Aliphatic Index 72.57

Aromaticity 0.1286

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3362.49

LogP -32.89

H-bond Donors 131.0

H-bond Acceptors 114.0

Rotatable Bonds 267.0

Heavy Atoms 570.0

Ring Count 12.0

Amide Bonds 74.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0286241 VERIFIED: NO

Provenance & Taxonomy

OrganismDanio rerio [Animal]

FamilyDefensin

Tax ID7955

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence