‹ ›
MYP_078188
← PREVIOUS NEXT → BACK
Basic Information
Gomesin c(1-18)[Gln1]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C93H158N36O24S4
Standard
Sequence
QCRRLCYKQRCVTYCRGR
Physicochemical Analysis
2292.74 Da
9.93
5.72
5.45
0.3176
-1.06
0.47
-0.64
36.59
37.78
0.1111
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1040.41
-12.05
44.0
34.0
77.0
157.0
2.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0382826 VERIFIED: NO
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0384567 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
2-15, 6-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiparasitic Antimalarial Antic
Staphylococcus epidermidis
0.8-1.6 μM
MIC
PaperIsolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family. J Biol Chem. 2000 Oct 27;275(43):33464-70. doi: 10.1074/jbc.M001491200. PMID: 10942757. PMID10942757 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10942757/
RECORD: Rec_0388212 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans MDM8
2.56-5.12 μM
MIC
PMID22865764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22865764/
RECORD: Rec_0391913 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
2-15, 6-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiparasitic Antimalarial Antic Hemolytic
human erythrocytes
PaperIsolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family. J Biol Chem. 2000 Oct 27;275(43):33464-70. doi: 10.1074/jbc.M001491200. PMID: 10942757. PMID10942757 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10942757/
RECORD: Rec_0397482 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Tachyplesin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
megaterium, B. thuringiensis, Enterococcus faecalis, Listeria monocytogenes, Micrococcus luteus, P. acidolacrici, Staphylococcus aureus, Staphylococcus epidermidis, S. haemolyticus, s. saprophyticus, Streptococcus pyogenes, N. asteroides
0.4-12.5 μM
MIC
PaperIsolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family.
FIRST PREV 1 ... 10 11 12 13 NEXT LAST
Showing 5 records on this page · Page 12 of 13