Peptide Database

Peptide NameNeurotoxin BmK-M9

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC304H466N92O90S8

DescriptionStandard

        VRDAYIAKPENCVYHCATNEGCNKLCTDNGAESGYCQWGGRYGNACWCIKLPDRVPIRVPGKCH
    

Molecular Weight7106.03 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0286

GRAVY Index-0.52

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index27.28

Aliphatic Index 56.41

Aromaticity 0.0938

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2926.03

LogP -32.07

H-bond Donors 108.0

H-bond Acceptors 102.0

Rotatable Bonds 224.0

Heavy Atoms 494.0

Ring Count 14.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281765 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense