Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC886H1404N258O263S11

DescriptionStandard

        MKKGIIACSIAAIISLAATLWPQALRTSPEAQLKMAKYEDCRKTPYYCPAGVLTVGIGSTSKVENRQYAEGEIAERWVNDLMRAEKCTNREFNGAAAPQKVFESMTDANFNVGCTGLGWYTTKDGQKVRTTLWRHAQAGNWKGVCDRLTDFVNSAGKRSQGLVNRRTDFQAWCLSEPALKGAK
    

Molecular Weight20230.91 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0466

GRAVY Index-0.42

Hydrophobic Moment 0.83

Boman Index-0.06

Instability Index40.39

Aliphatic Index 68.36

Aromaticity 0.0874

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8470.35

LogP -98.89

H-bond Donors 304.0

H-bond Acceptors 284.0

Rotatable Bonds 673.0

Heavy Atoms 1418.0

Ring Count 29.0

Amide Bonds 199.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0120691 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0299582 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage ST101-KPC2phi6.2 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic