Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2566H3979N643O745S20

DescriptionStandard

        MCTKMVQVLWGCFLLWNVYISSAWITHPGIKARATQRALDYGVQAGMEMIEQMAKERNLPDLKGSESLEFLKVDYVNYNFSNIKIHAFSFPNTSLAFVPGVGIKALTNHGTANISTNWEVKSPLFQDSGGADLFLSEVYFMGILNLARNDFGQPTLELQDCHAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIIGEVEALNANLSMLEVLTKIDNYTLLDYSLMSSPEITENYIDLNLKGVFYPLENLTDPPFSPVPFVLPERSDSMLYIGISEYFFRSASFAHFAAGAFNVTLSTKEISSHLVRNSQGVGNILSRIAEIYILSQPFMIRIMATEPPVISLLPGNFTLDIPASIMLLTQSENSTAESIVSMDFVASTSVSLVILGQRLICSLSLNRFRLSLPESNHNNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPSPDKISFVNSDVEVLEHFLLISTDLKYETPVKQQPSFYGWEGLNLINGQWGGKPVP
    

Molecular Weight56397.20 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-17.51

Net Charge (pH 7.4) -18.47

Charge Density (pH 7.0) -0.0345

GRAVY Index0.14

Hydrophobic Moment 0.67

Boman Index0.18

Instability Index44.83

Aliphatic Index 102.29

Aromaticity 0.1006

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262423 VERIFIED: NO

Provenance & Taxonomy

OrganismPipistrellus kuhlii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria