Peptide Database

Peptide NameBrevinin-2TC

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC144H235N37O37S3

DescriptionStandard

        GIWDSIKTFGKKFALNIMDKIKCKIGGGC
    

Molecular Weight3172.83 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.1288

GRAVY Index0.08

Hydrophobic Moment 0.66

Boman Index0.12

Instability Index23.72

Aliphatic Index 84.14

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1208.18

LogP -8.78

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 112.0

Heavy Atoms 221.0

Ring Count 4.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321474 VERIFIED: YES

Provenance & Taxonomy

OrganismRana amurensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)