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MYP_078124
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Basic Information
Papillosin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C153H243N45O38
Standard
Sequence
GFWKKVGSAAWGGVKAAAKGAAVGGLNALAKHIQ
Physicochemical Analysis
3320.84 Da
10.60
4.84
4.58
0.1424
0.25
0.47
0.26
13.51
86.47
0.0882
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1320.39
-12.46
46.0
44.0
110.0
236.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0237690 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus megaterium
0.05-0.1 μM
MBC
PaperHalocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa.
RECORD: Rec_0246617 VERIFIED: NO
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Hemolytic Non-ribosomal
A.viridans, Bacillus megaterium, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Micrococcus luteus, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella Typhimurium
Qualitative functional evidence
PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/; https://www.uniprot.org/uniprotkb/P86416/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0256703 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Papillosin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Pept Sci. 2009 Jan;15(1):48-55. | http://www.ncbi.nlm.nih.gov/pubmed/19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0268463 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacteria (Native, Synthetic): Enterobacter aerogenes 30
PaperPubMed PMID: 19085906 PMID19085906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19085906/
RECORD: Rec_0277178 VERIFIED: YES
Provenance & Taxonomy
Halocynthia papillosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis
0.78-1.56 μM
MBC
PaperHalocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa.
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