Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC373H623N111O95S8

DescriptionStandard

        MKSLLLVLVVLVLLSCVPPVRSGPNTYIRTAFSTCWGGKGVCRKLCGGNEDYHIFCDVRRLCCVNKKLLNVRVRR
    

Molecular Weight8439.14 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.13

Charge Density (pH 7.0) 0.1269

GRAVY Index0.33

Hydrophobic Moment 0.64

Boman Index0.02

Instability Index55.11

Aliphatic Index 111.47

Aromaticity 0.0667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3326.45

LogP -29.07

H-bond Donors 127.0

H-bond Acceptors 114.0

Rotatable Bonds 279.0

Heavy Atoms 587.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0128549 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera pardus (Leopard) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin