Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2352H3710N584O678S18

DescriptionStandard

        MVCLWCVLVLLTLLPASQSTDAGVKVRLTQKALEYGQNIGITYLQQKLGTIKVPDISGSESVFPIGEVQYRVTGMQIVSLGLPQSAVGLVPGTAVSFSIGNAFINMHGNWRVKYSNFIKDSGSFDLSVNDLTISTSIAIRSDETGRPAVNSAGCSATVGNTKIKLHSGASWLYNLFSFFTDKILGKALERQICPLVVETIVEMNHYLKSLNVLAEVDEYAEIEYPMVASPVISKSSIDFSLMGEFHSTGQHHWSAAPFSPTAFSLPPQDSNMLYIGLSAFTVNSAAFVYHTAGALSLYITDDLIPPSIPIRLSTITFGAFIPQIAKMYPGLMMKLHMKTAKVPIITFQPNNVTVQASSTVTAYAIQPNATLSPLFVLNLDASVSARIYVTGLKVAGSVTLNSIDITLGTSYVGPFQVKSLDNIFVMVLKVAVLPMVNAYFEKGYPLPAIGEIDLINTQLQVLKDYMLLGTDLKFSR
    

Molecular Weight51593.29 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.82

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0017

GRAVY Index0.34

Hydrophobic Moment 0.61

Boman Index0.23

Instability Index30.69

Aliphatic Index 105.86

Aromaticity 0.0924

Extinction Coeff. Reduced 48820.00

Extinction Coeff. Oxidized 49070.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003353 VERIFIED: NO

Provenance & Taxonomy

OrganismChanos chanos (Milkfish) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria