Peptide Database

Peptide NameaStAx-41R

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC99H167N43O20

DescriptionStandard

        RRWPRRILHHDVRRVAR
    

Molecular Weight2279.66 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.94

Net Charge (pH 7.4) 5.63

Charge Density (pH 7.0) 0.3491

GRAVY Index-1.49

Hydrophobic Moment 0.78

Boman Index-0.78

Instability Index151.08

Aliphatic Index 85.88

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1063.88

LogP -8.94

H-bond Donors 42.0

H-bond Acceptors 28.0

Rotatable Bonds 74.0

Heavy Atoms 162.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371157 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAxin-derived

Tax ID32630

Structure & Mods

Confighydrocarbon-stapled side-chain cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

C-TermAmidation

Other ModsStapled: Ⓧ(6) and Ⓧ (10) are cross-linked by hydrocarbon stapling

Bio-Activity Profile

Function

Anticancer Antimicrobial Antibacterial