Peptide Database

Peptide NameFMRFamide-related neuropeptide, HDYMRFamide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC39H53N11O10S

DescriptionStandard

        HDYMRF
    

Molecular Weight867.97 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0254

GRAVY Index-1.30

Hydrophobic Moment 0.64

Boman Index-0.29

Instability Index69.00

Aliphatic Index 0.00

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 356.93

LogP -1.53

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 26.0

Heavy Atoms 61.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120285 VERIFIED: NO

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0188591 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0306448 VERIFIED: NO

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyFMRFamide related peptide

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0307879 VERIFIED: NO

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyHDYMRF-amide

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour