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MYP_078032
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Basic Information
ASABF-ALPHA
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
75 amino acids
C325H532N114O100S10
Standard
Sequence
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGRRHS
Physicochemical Analysis
7957.05 Da
9.49
7.90
7.48
0.1053
-0.60
0.63
-0.19
55.53
38.93
0.0400
5500.00
6000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3445.40
-49.92
132.0
120.0
262.0
549.0
11.0
77.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028664 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperKato Y., Komatsu S.;. "ASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suum. Purification, primary structure, and molecular cloning of cDNA."; J. Biol. Chem. 271:30493-30498. Evidence URLhttps://www.uniprot.org/uniprotkb/P90683/entry
RECORD: Rec_0035620 VERIFIED: NO
Provenance & Taxonomy
Ascaris suum [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0051354 VERIFIED: YES
Provenance & Taxonomy
Ascaris suum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Proteus vulgaris ATCC 13315
10 μg/mL
IC50
PMID8940016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8940016/
RECORD: Rec_0052677 VERIFIED: YES
Provenance & Taxonomy
Ascaris suum [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Proteus vulgaris ATCC 13315
10 μg/mL
IC50
PaperPubMed PMID: 8940016 | PubMed PMID: 10991847 PMID8940016;10991847 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8940016/
RECORD: Rec_0062749 VERIFIED: YES
Provenance & Taxonomy
Ascaris suum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suum. Purification, primary structure, and molecular cloning of cDNA.
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